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The season picks up from the season 4 finale two to three months after the events of finding out Ian's bipolarity and Fiona's release from prison. Fiona begins a new relationship with a skilled member of a rock 'n' roll band while juggling her new job at Patsy's Pies, where she has flirtatious encounters with her boss, Sean. Lip is home from college for the summer, and is torn between two worlds as his loyalty to the South Side is questioned while gentrification comes to the neighborhood. Ian's declining mental health raises the concerns of Mickey and the rest of the Gallaghers, yet he remains in denial of his condition. Debbie continues to struggle with the pains of adolescence and Carl begins a new business venture as a drug-dealer. Sammi becomes more involved in the lives of her half-brothers and sisters while Frank struggles with sobriety following his recent liver transplant.
